Gastric Syphilis
نویسندگان
چکیده
A 48-year-old Japanese man presented with epigastralgia, pyrosis, and regurgitation. A physical examination revealed tenderness in the epigastrium. Rapid plasma reagin and Treponema pallidum tests were positive, with titers of 1:64 and 1:10,240, respectively. Gastroscopy revealed multiple geographic, irregular ulcers from the gastric body to the pylorus and duodenum (Picture 1). Gastric biopsies were performed, and a histopathological analysis showed severe inflammatory cell infiltration. Immunohistochemistry (Picture 2), a conventional polymerase chain reaction (PCR), and a real-time PCR showed the presence of T. pallidum in the gastric tissues. He was treated with amoxicillin, which led to the resolution of his clinical complaints. Gastric syphilis is usually observed after secondary syphilis, but its incidence is extremely low (1). The endoscopic findings typically reveal mucosal edema, erosion, and superficial ulcers (2). In conclusion, when gastroscopic findings, such as those described in this report, are observed, gastric syphilis should be considered as an important differential diagnosis in view of its nonspecific presentation.
منابع مشابه
Gastric Syphilis Mimicking Adenocarcinoma: A Case Report
Syphilis is an unexpected diagnosis in the stomach, and the reduced incidence of syphilis has made its clinical presentation less widely appreciated. We report a 43-yr-old man suffering from epigastric tenderness with an initial diagnosis of gastric carcinoma; gastric syphilis was confirmed by demonstrating spirochetes in a gastric biopsy specimen by silver impregnation. Excessive lymphoplasmac...
متن کاملGastric syphilis - Case report*
Gastric syphilis is an uncommon extracutaneous manifestation of syphilis, occurring in less than 1% of patients, presenting nonspecific clinical manifestations. In general, it occurs on secondary stage. The critical point is the recognition of the syphilitic gastric involvement, without which there may be incorrect diagnosis of malignancy of the digestive tract. In this report, a case of second...
متن کاملGastric syphilis
Syphilis is a chronic systemic infectious disease. Gastric involvement is uncommon. We report of a 55-year-old female patient with a history of epigastric pain and a diagnosis of Syphilis confirmed by main clinical symptoms, tolulized red unheated serum test(TRUST) and treponema pallidum hemagglutination assay(TPHA). At the same time, we still reported gastric involvement about syphilis in this...
متن کاملSubacute Wernicke's encephalopathy due to gastric syphilis.
In a patient who presented with subacute Wernicke's encephalopathy the underlying gastric lesion was found to be due to syphilis.
متن کامل